If upon launching ZBrush your computer crashes with the BSOD (Blue Screen of Death), the most likely issue is your motherboard BIOS and drivers being out of date.
All motherboards have the ability to have their BIOS flashed/updated. This allows them to receive updates to fix any code-based issues that might arise with the motherboard after it has shipped. In some cases, it also enables new features that in turn extend to the operating system.
We cannot give you specific instructions for how to update your BIOS because it varies from board to board. Please check with your motherboard's support site for instructions. There may also be downloads of newer versions of the driver software that runs the components that are pre-installed on your motherboard. Examples include your USB controller and Ethernet adapter. Be sure to check for any driver updates that are shown on your motherboard maker's website.